Contents of Erythorbic Acid in the Tissues of Guinea Pigs Intraperitoneally Administered Erythorbic Acid.

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Contents of erythorbic acid in the tissues of guinea pigs intraperitoneally administered erythorbic acid.

The contents of ascorbic acid (AsA) and erythrobic acid (ErA) in the tissues of guinea pigs intraperitoneally injected with AsA and/or ErA were determined to learn the difference in their retention in the tissues. After 10 d of AsA depletion, the guinea pigs were intraperitoneally injected with 5 mg of AsA, or 5 mg of ErA, or 5 mg of each. At day 5 of repletion, the guinea pigs were killed and ...

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Effect of graded doses of erythorbic acid on ascorbic acid content of tissues of guinea pigs.

The effect of graded doses of erythorbic acid (ErA) on the content of ascorbic acid (AsA) in the tissues of guinea pigs administered AsA was studied. The guinea pigs were administered 5 mg AsA and 1, 5, 20, and 100 mg ErA; or 1 mg AsA and 1 and 20 mg ErA; or 20 mg AsA and 20 mg ErA for 16 days. The animals were then sacrificed, and the liver, adrenal glands, spleen, and kidneys were removed to ...

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Effect of smoking on erythorbic acid pharmacokinetics.

Considerable evidence exists that smoking significantly lowers the concentration of plasma antioxidants. While for most antioxidants this effect appears to result mainly from altered dietary habits, ascorbic acid has recently been shown to be depleted by smoking per se. However, the direct cause of ascorbate depletion remains unclear. Erythorbic acid is a stereoisomer of ascorbic acid commonly ...

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Erythorbic acid is a potent enhancer of nonheme-iron absorption.

BACKGROUND Erythorbic acid, a stereoisomer of ascorbic acid with similar physicochemical properties, is widely used as an antioxidant in processed foods. OBJECTIVES The aims of the present study were to evaluate the effect of erythorbic acid on iron absorption from ferrous sulfate at molar ratios of 2:1 and 4:1 (relative to iron) and to compare the effect of erythorbic acid directly with that...

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Intravenous (iv) infusion of high-dose ascorbic acid (AA) has been used as a treatment for cancer patients. The tumoricidal action of AA occurs due to its prooxidant effect. Erythorbic acid (EA), one of the AA epimers, has reduced vitamin C activity, while the antioxidant activity of EA is similar to that of AA. Currently, other physiological and pharmacological functions of EA are not well kno...

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ژورنال

عنوان ژورنال: Journal of Nutritional Science and Vitaminology

سال: 1998

ISSN: 0301-4800,1881-7742

DOI: 10.3177/jnsv.44.573